Embryo development starts when a single egg cell is fertilized and starts dividing continuously. Initially a chaotic cluster, it gradually evolves into a highly organized structure. Scientists have ...

Live imaging of embryos at different stages. Chromosomes are labeled in magenta. 4-cell sister blastomeres are shown, along with 3D-reconstructed images of 2-to-4-cell and 4-to-8-cell divisions.

New findings offer insight into why some embryos fail to develop past zygotic genome activation (ZGA), pointing to an unexpected root of human infertility. A critical point in early development is ...

Researchers at Sinai Health have found that a critical transition in early human development is regulated not by our genes, but by DNA elements called transposons that can move around the genome. The ...

A lot happens in the first month of human embryo development as a single cell morphs into multitudes. Yet despite its significance, this period is basically a “black box” to researchers, says stem ...

A new discovery by researchers at the RIKEN Center for Biosystems Dynamics (BDR) in Japan upends decades of assumptions regarding DNA replication. Led by Ichiro Hiratani and colleagues, the ...

In A Nutshell Egg geometry drives development: The curved shape of a zebrafish egg causes unequal cell divisions, creating larger cells near the animal pole and smaller cells at the margin—a size ...

A discovery upends decades of assumptions regarding DNA replication. The study show that DNA replication in early embryos is different from what past research has taught, and includes a period of ...