A review found that CD4/CD8 ratio could be used as a prognostic marker for mortality in patients with HIV, though future studies need to be done to confirm these findings. Clinical practices can ...

Chimeric antigen receptor (CAR) T-cell therapy-associated immune-related adverse events (CirAEs) were associated with a high ...

The researchers concluded that the interplay between CD4 and CD8 T cells creates an anti-inflammatory environment that is hostile to Mtb and, as a result, limits bacterial growth and disease severity.

Higher levels of CD4-positive naïve T cells in patients receiving CAR T-cell therapy for multiple myeloma are associated with longer PFS, suggesting T-cell composition may serve as a biomarker to ...

The rollout of vaccines against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pathogen has led to a significant reduction in coronavirus disease 2019 (COVID-19) cases, ...

Osaka, Japan – Much like ripples on the water can betray powerful currents below the surface, small changes in our bodies can sometimes be an indicator of a serious condition. Now, researchers from ...

Decades after its discovery, the emerging view of idiopathic CD4 lymphocytopenia (ICL) -- popularly dubbed "AIDS without HIV" -- is that it may be more homogeneous than originally thought, despite ...