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An ultimate guide to analyzing challenging biological samples with confidence

Discover practical strategies for analyzing challenging biological samples, from low-input and degraded specimens to complex matrices.
Nature

Differences in age-related distribution of CSF alpha-synuclein seeding and Alzheimer profiles between PD with and without GBA1 variants

Among CSF samples from PD wildtype, 175 (93%) were positive for α-Syn. CSF-based AD profiles were identified in 10 (5%) samples. Higher prevalence of AD profiles were associated with increased age (p ...
Nature

Subarachnoid haemorrhage or traumatic lumbar puncture. Differentiation by cerebrospinal fluid parameters in a multivariable approach

Spontaneous subarachnoid haemorrhage (SAH) is a severe life-threating neurological disease which accounts for approximately 5–10% of all strokes and bears the risk of significant morbidity and ...