One of the most prevalent base modifications involved in decoding is uridine 5-oxyacetic acid at the wobble position of tRNA. It has been known for several decades that this modification enables a ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, No. 10 (March 10, 2015), pp. 3038-3043 (6 pages) Premature termination codons (PTCs) in an mRNA ORF ...

The genetic code is made up of a total of 64 base triplets or codons. At least one codon encodes the information for each of the 20 amino acids used in the synthesis of proteins during translation.

The genetic code is a set of instructions that direct the translation of DNA into 20 amino acids, the basic units of proteins in living cells. The genetic code is made up of codons, which are ...