When DNA breaks, cells must repair it accurately to prevent harmful mutations. Researchers have discovered that during a key repair process called homologous recombination, the cell uses loops in its ...

Changes in genes have been linked to the development of different diseases for a while. However, it's not exactly clear what ...

Among the many marvels of life is the cell's ability to divide and thus enable organisms to grow and renew themselves. For this, the cell must duplicate its DNA—its genome—and segregate it equally ...

DNA has been known to form loops, and these loops have been thought to influence gene expression, recombination, and DNA repair. But according to a new study, DNA loops are rare and fleeting.

Two protein complexes carry the major responsibility for the spatial organization of chromosomes in our cell nuclei. DNA tension plays a surprising role in this. Nanoscientists now publish how they ...

Not all DNA looks like the familiar double helix. Sometimes, parts of our genetic code fold into unusual shapes under certain conditions. One such structure known as a G-quadruplex (G4) looks like a ...

Supercoiling and looping can transmit mechanical stress along the DNA backbone that can promote the separation of the strands of the double helix at specific distant sites, exposing the DNA bases, ...

In earlier work, Erez Lieberman Aiden of Baylor College of Medicine in Houston and colleagues figured out that a specific stretch of DNA acts as a stop sign that sits at the ends of the loops DNA ...

Among the many marvels of life is the cell's ability to divide and thus enable organisms to grow and renew themselves. For this, the cell must duplicate its DNA – its genome – and segregate it equally ...

As people grow older, their immune systems do not simply slow down, they often become locked into a simmering, ...