Homologous recombination is a DNA repair mechanism that counteracts double-stranded breaks in DNA. Researchers at Kindai University have recently revealed how the Sae2 protein coordinates with the ...

A team of international researchers at the University of Oxford (Oxford) and Nanyang Technological University, Singapore (NTU Singapore), has discovered a new process for repairing damaged DNA that is ...

Researchers have discovered a DNA repair mechanism that advances understanding of how human cells stay healthy, and which could lead to new treatments for cancer and premature aging. Researchers at ...

The human genome is contained within the nucleus of cells. The genome is well protected, but many things can cause DNA damage, including aging, some drugs, and environmental factors like UV rays or ...

A research team led by Professor ZHAO Guoping at the Hefei Institutes of Physical Science of the Chinese Academy of Sciences, has unveiled a crucial mechanism that helps regulate DNA damage repair, ...

DNA repair is essential for the maintenance of genomic stability and its failure can lead to human disease. Various DNA repair systems exist, such as base excision repair, nucleotide excision repair, ...

Researchers decode repair mechanism during transcription of genetic information. Cockayne syndrome is a severe autosomal recessive disorder caused by defective DNA repair mechanisms. People with the ...

Researchers at the University of Toronto have discovered a DNA repair mechanism that advances understanding of how human cells stay healthy, and which could lead to new treatments for cancer and ...

The DNA inside our cells is constantly being damaged, and one of the worst kinds of damage is a double-strand break—when both sides of the DNA helix are cut at once. Healthy cells can normally fix ...

Not all DNA looks like the familiar double helix. Sometimes, parts of our genetic code fold into unusual shapes under certain conditions. One such structure known as a G-quadruplex (G4) looks like a ...