Cornell researchers have found that a new DNA sequencing technology can be used to study how transposons move within and bind to the genome. Transposons play critical roles in immune response, ...
In a study published in Cell, a research team led by ZHANG Yong'e and WANG Haoyi from the Institute of Zoology of the Chinese Academy of Sciences has characterized the diversity of DNA transposons and ...
Understanding transposons provides a new starting point to generate more powerful gene editing tools
CRISPR has ushered in the era of genomic medicine. A line of powerful tools has been developed from the popular CRISPR-Cas9 to cure genetic diseases. However, there is a last-mile problem – these ...
Conventional CRISPR–Cas systems maintain genomic integrity by leveraging guide RNAs for the nuclease-dependent degradation of mobile genetic elements, including plasmids and viruses. Here we describe ...
Our genome, any geneticist will tell you, can be a chaotic place. In addition to holding the necessary instructions for life, our DNA also houses droves of mobile genetic snippets that can ...
CU Boulder researcher Edward Chuong recently received an international award for his lab’s work studying transposons in the human genome Our genome, it turns out, is full of freeloaders—selfish ...
The winters in Ithaca, NY, are long, snowy, and bitterly cold. The Cornell University students who endure them can be overheard discussing “Ithacation”—a mix of snow, hail, rain, and slush—as they ...
Restricted access to genome-editing technologies poses serious challenges for countries like India that urgently need such ...
The first transposon that can determine survival in mammals has been identified, raising questions about evolution and fertility in the class. Transposons are DNA sequences initially incorporated into ...
Nearly half of our DNA has been written off as junk, the discards of evolution: sidelined or broken genes, viruses that got stuck in our genome and were dismembered or silenced, none of it relevant to ...
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