This Brush Up is sponsored by Cayman Chemical. Learn more about chemical inhibitors of histone modification. Histone modification affects how tightly DNA wraps around histone proteins, yielding ...
Researchers have discovered that a DNA modification called 5-formylcytosine (5fC) functions as an activating epigenetic switch that kick-starts genes in early embryonic development. This finding ...
Epigenetics, the study of changes in gene function that do not involve alterations to the DNA sequence, plays a pivotal role in understanding the complex interplay between genetics and the environment ...
Maternal prenatal stress related to natural and human-made disasters can lead to epigenetic modifications in offspring, ...
Epigenetics is a rapidly growing field of study that focuses on the heritable changes in gene expression that occur without alterations to the underlying DNA sequence. These changes are caused by ...
Machine learning models reveal that histone marks are predictive of gene expression across human cell types and highlight important nuances between natural control and the effects of CRISPR-Cas9-based ...
A recent study led to the development of a powerful epigenetic editing technology. The system unlocks the ability to precisely program chromatin modifications at any specific position in the genome, ...
The team of Professor Christof Niehrs at the Institute of Molecular Biology (IMB) in Mainz, Germany, has discovered that a DNA modification called 5-formylcytosine (5fC) functions as an activating ...
Type 1 diabetes is an autoimmune disease in which the immune system destroys the body’s own insulin-producing beta-cells in the pancreas, leaving patients with a lifelong dependency on external ...
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