In this review, we first provide a brief overview of frailty, including biologic mechanisms, measurement, and clinical management. This overview is followed by a discussion of approaches to ...

In a groundbreaking study, scientists have mapped the most detailed genetic blueprint yet of frailty – the age-related decline in resilience that affects around 40% of people aged 65 and above, ...

Physical frailty is strongly associated with an increased dementia risk in older adults, and according to researchers, the link may be causal. In an analysis of nearly half a million UK Biobank ...

Frailty — a clinical syndrome characterized by decreased physiological reserve and increased vulnerability to stressors — has traditionally been associated with geriatric medicine but has profound ...

Frailty begins to accelerate 4 to 9 years before dementia onset and may help identify at-risk populations for prevention strategies. Study: Frailty Trajectories Preceding Dementia in the US and UK.

Please provide your email address to receive an email when new articles are posted on . DESTIN, Fla. — Rheumatologists are uniquely positioned to define and manage sarcopenia and frailty, according to ...

The frailty index (FI), developed by our group, is one of the leading paradigms for understanding frailty at population, personal, organ, and tissue levels (with cellular deficit evaluation in ...

Double-Blind, Placebo-Controlled, Randomized Phase III Trial Evaluating Pertuzumab Combined With Chemotherapy for Low Tumor Human Epidermal Growth Factor Receptor 3 mRNA–Expressing Platinum-Resistant ...