Co-founded by Jennifer Doudna and Fyodor Urnov, the company intends to simultaneously develop many gene editing treatments for rare conditions by using the agency’s “plausible mechanism” pathway.

This study, led by Dr. Panpan Jiang and collaborators at Tongji Medical College, explores the critical role of the Dedicator of Cytokinesis 8 (DOCK8) gene in the differentiation of helper T cells, ...

The Organoid group at the Hubrecht Institute have identified a new link between FBXW7 mutations and EGFR signaling activity. The FBXW7 gene is commonly mutated in colorectal cancer and such mutations ...

Australian researchers have discovered that a single mutation in the DNA sequence for a methylation enzyme dysregulates key tumor-suppressing pathways, opening up new avenues for blood cancer ...

Validation of a 15-Gene Prognostic Signature in Metastatic Clear Cell Renal Cell Carcinoma Despite the significance of immune checkpoint inhibitors (ICIs) in solid tumor treatment, identifying ...

NOTE. P < .00357 represents statistical significance after the Bonferroni correction. Abbreviations: MAPK, mitogen-activated protein kinase; NA, unable to be calculated; NR, not reached; OS, overall ...

Researchers at Weill Cornell Medicine report that a rare gene mutation that delays Alzheimer’s disease does so by damping inflammatory signaling in brain-resident immune cells in a preclinical study.

(Left) Distribution of gender among never-smoking lung cancer patients analyzed in this study with predominance of females. (Middle) Screening results for genetic mutations in never-smoking lung ...

Please provide your email address to receive an email when new articles are posted on . Low-dose aspirin significantly reduced risk for colorectal cancer recurrence among patients with mutations in ...

As the body ages, it is normal for changes in cells to occur. "Cells divide every day and mutations happen," said Emma M. Groarke, M.D., an attending hematologist and researcher in NHLBI's ...