Understanding human gene function in living organisms has long been hampered by fundamental differences between species.

Taconic Biosciences, Inc., a global leader in genetically engineered rodent models (GEMs) and humanized immune system (HIS) mouse models, today announced the acquisition of TransCure bioServices SAS, ...

A Ludwig Cancer Research study has identified a specific mode of fat uptake by immune cells within tumors that serves as a metabolic checkpoint against anti-cancer immune responses. Harnessing that ...

Figure 1: VIP protects against CD4 + T cell depletion in humanized mice resulting from challenge with CCR5-tropic or transmitted founder HIV strains. Figure 2: VIP prevents mucosal transmission of ...

In vivo models of human immunity in human tumor-bearing mice are frequently used to study mechanisms of targeted immunotherapies, safety, and efficacy. In a recent webinar Jenny Rowe, PhD, Scientist ...

Please provide your email address to receive an email when new articles are posted on . The FDA approved the first chimeric antigen receptor therapy in 2017, authorizing tisagenlecleucel for treatment ...

A severe organ shortage plagues the progress of organ transplantation. One solution may be to generate human organs in other large mammals, however, that process is challenging. Now, researchers have ...

Why do 80 to 90% of people infected with COVID-19 experience only mild cases while 10 to 20% face more severe or life-threatening symptoms? Researchers in the lab of Yale’s Richard Flavell decided to ...

Researchers have created a functional 'humanized' liver in living mice that will help scientists find human-specific mechanisms for regulating cholesterol levels and potentially for treating chronic ...

Mice are commonly used as models of human disease, helping scientists to understand the workings of complex pathologies and develop safe and efficacious drugs. It is now possible to create a range of ...

Chinese military researchers were part of a project that created mice with “humanized” lungs — apparently to test the infectiousness of various viruses, according to a blockbuster report Thursday. The ...