Currently, only 10% of the drugs that enter Phase I receive marketing approval from the U.S. Food and Drug Administration (FDA), with unmanageable toxicity accounting for approximately 30% of the ...

Transcriptome-based NGS outperforms traditional viral testing with superior sensitivity, detecting viruses including novel ...

Well before a human receives the first dose of an experimental drug, it’s evaluated in an animal to test for toxicity. Monkeys are often chosen for their genetic similarities to humans, and safe ...

Using the Liver-on-a-chip hepatic co-culture model (assessed by CN-Bio’s partners at the US FDA), the DILI in vitro Service can screen the gene editing reagents, antibodies, small molecules, and ASO ...

For decades, animal models have been the gold standard for preclinical testing of potential drugs. Yet, even the best animal models are not perfect. For example, small rodent species with engrafted ...

For decades, preclinical testing in mice, rats, and nonhuman primates has been a crucial part of drug development, an important although not infallible way to ensure some measure of safety for human ...