Doubly uniparental inheritance (DUI) of mitochondrial DNA (mtDNA) represents a rare and intriguing deviation from the standard model of strictly maternal inheritance. In bivalves, DUI manifests as the ...

Back in the 19 th century, as the US grappled with the aftermath of the Civil War, Jesse James, leader of a notorious gang of outlaws, rose to prominence. He robbed banks and trains for over a decade ...

The tiny little powerhouses of our cells, the mitochondria, are unique among organelles because they carry their own tiny ...

For years we’ve been told that MtDNA (maternal DNA) is passed from mother to children, both male and female, but only ...

In the study, the group demonstrated that preventing USP30 from acting with the inhibitor compound 39 (CMPD39) creates a "window of elimination" for altered mitochondrial DNA shortly after ...

Geneticists looking inside the nuclear genome for mutations that contribute to disease have long relied on a principal known as constraint modeling, which allows researchers to assess the degree of ...

Management of mitochondrial-related heart disease relies on multidisciplinary care and symptom control, as targeted gene-editing therapies are limited.