For patients with acute ischemic stroke due to a large-vessel occlusion (LVO), administering intra-arterial thrombolytics after successful endovascular thrombectomy does not significantly improve ...

Just a month after trial results appeared to dampen prospects for the use of intra-arterial thrombolysis on top of stroke thrombectomy in patients with large-vessel occlusions (LVOs), two new trials ...

Intra-arterial (IA) alteplase was associated with superior 90-day functional outcomes than standard therapy alone in Chinese patients with large-vessel occlusion (LVO) stroke who had achieved ...

Two randomized trials found that intra-arterial urokinase and tenecteplase did not improve functional outcomes after mechanical thrombectomy in selected stroke patients. However, these results do not ...