Bone marrow contains stem cells that make the many types of blood cell our immune system needs. The diversity of these blood cells drops as we age, and this is thought to contribute to some aspects of ...

In a recent study published in the journal Science Advances, a team of Chinese researchers used murine models to investigate whether immune rejuvenation through the transplantation of young bone ...

As anti-amyloid approaches continue to yield meager benefits for people with Alzheimer’s disease, therapies targeting neurofibrillary tangles are getting more attention. In the October 1 Nature ...

To investigate the mechanism by which hypoxia-reoxygenation (HR) mediates macrophage polarization to the M1 phenotype and then mediates cardiomyocyte (CM) pyroptosis through exosome release. Mouse ...

Microscopy images of monocytes in the brain of a mouse after a heart attack. Schematic of hypothesized mechanism: after a heart attack, monocytes are released from the bone marrow and recruited to the ...