Toward the goal of generating high-quality embryo models in vitro, this study establishes a stepwise protocol to derive trophectoderm-like cells from mouse extended pluripotent stem (EPS) cells. These ...
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Role of LADs and Epigenetic Pathways in Nuclear Architecture During Early Mouse Embryo Development
A recent study published in Cell investigates how lamina-associated domains (LADs) contribute to nuclear genome organization in early-stage mouse embryos. Focusing on the zygote and two-cell stages, ...
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DNA from ancient viral infections helps embryos develop, mouse study reveals
A stretch of viral DNA in the mouse genome gives cells in early-stage embryos the potential to become almost any cell type in ...
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