The demand for producing therapeutic recombinant proteins is generating a renewed interest in perfusion cell culture technologies, leading to the development of cell culture media that can support ...

As the GEN article “Prospects for Downstream Production” notes, perfusion cell culture is most often associated with upstream continuous processing operations. The two main perfusion techniques are ...

In dense cell perfusion cultures, the surfactant Pluronic F-68 (PF-68) is often added to protect cells from the damage caused by shear stress (such as agitation or bursting gas bubbles). Extremely ...

Erbi's differentiated 2 ml micro-bioreactor platform technology, Breez ™, enables rapid lab testing for bioprocessing scale up Allows MilliporeSigma to offer full range of bioreactors, from 2ml to ...

Raman spectroscopy has a wide range of applications as it can detect subtle changes in intricate aqueous systems, including the analysis of biopharmaceutical processes such as cell growth in ...

Process Raman spectroscopy is a commonly used tool for real-time monitoring and control in bioprocessing. This article outlines the role of cultured cells in biologics manufacturing and why developing ...