Researchers report that they are at the forefront of discovering and mapping out the complexities of the structures involved in a process of pri-miRNA biogenesis. For the first time, the team has ...

MicroRNAs (miRNAs) are endogenous noncoding RNAs (∼22 nt) that regulate target gene expression at the post-transcriptional level in the cytoplasm. Recent discoveries of the presence of miRNAs and ...

In humans (as well as all other organisms) genes encode proteins, which in turn regulate all the different specific cellular functions of the body. The genetic information found in our DNA is first ...

In a study published in Nature, researchers report that Smad proteins regulate microRNA processing. Understanding the role of Smad proteins enables researchers to investigate abnormal miRNA processing ...

RNA interference (RNAi) is a post-transcriptional gene regulatory system that promotes gene silencing through the use of non-coding RNA molecules called microRNAs. These short RNA sections are taken ...

It's a big year for microRNAs. The 2024 Nobel Prize in Physiology or Medicine went to Victor Ambros and Gary Ruvkun, who discovered the first microRNA in 1993. Today, we know that humans make more ...