Ahmet Coskun's lab has developed iseqPLA to map protein interactions. An artistic rendering of sub-cellular activity: The cell membrane is seen at the top, nucleus on the bottom/right. Protein pairs ...

Proximity labeling has emerged as a revolutionary technique for delineating the complex network of protein-protein interactions within living cells. By utilising engineered enzymes that mark proximate ...

Scientists have designed a publicly-available software and web database to break down barriers to identifying key protein-protein interactions to treat with medication. The computational tool is ...

One in every three FDA-approved drugs targets a single superfamily of receptors dotting the surfaces of human cells. From beta blockers to antihistamines, these essential, life-saving medications ...

The α-helix is one of the most common protein surface recognition motifs found in nature, and its unique amide-cloaking properties also enable α-helical polypeptide motifs to exist in membranes.

Tackling simple questions is not Nevan Krogan’s thing. Over the past few years, his research has focused on COVID-19, cancer, and most recently, autism spectrum disorder (ASD). As a professor of ...

In the early 1980s, David Gilmour, now an emeritus biochemistry and molecular biology professor at Pennsylvania State University, joined the laboratory of geneticist and biochemist John Lis as a ...