In the cerebral cortex, extrinsic and intrinsic excitatory glutamatergic pathways terminate on principal glutamatergic neurons and local inhibitory GABAergic interneurons. Activation of these pathways ...

Researchers identify two key proteins that allow chandelier cells to connect with excitatory neurons. This "handshake" regulates brain signals and, when disrupted, may lead to epilepsy or autism.

The human brain's advanced cognitive capabilities are often attributed to our recently evolved neocortex. Comparison of human and rodent brains shows that the human cortex is thicker, contains more ...