Researchers developed a way to directly reprogram human glial cells into PV interneurons without passing through a stem‑cell stage.

Aside from reprogramming and transdifferentiation, the longer-existing approach to generating neurons and NSCs has been differentiating them from pluripotent cells, initially from embryonic stem cells ...

Using a blend of computer modeling, structural and cell-based studies, scientists at The Wertheim UF Scripps Institute have ...

GC Therapeutics, Inc. (GCTx), a biotechnology company created to scale and unlock the next generation of cell therapy-based medicines through its TFome™ cellular programming platform, today announced ...

Resting brain stem cells hardly differ from normal astrocytes, which support the nerve cells in the brain. How can almost identical cells perform such different functions? The key lies in the ...

When a neuron ages, it loses synaptic connections with other neurons, it is less able to transmit nerve impulses, and its metabolism is also altered. This process of neuronal ageing — inevitable with ...

The emergence of multicellular life roughly 700 million years ago was a pivotal event that shaped the evolution of life on Earth. Key to this transformation was the development of stem cells, which ...

A mature cell of one type can be turned into a mature cell of another type without the cell having to pass through an earlier stage of development. This is called direct reprogramming, a reliable but ...

When a neuron ages, it loses synaptic connections with other neurons, it is less able to transmit nerve impulses, and its metabolism is also altered. This process of neuronal aging — inevitable with ...

Immune cells called B cells make antibodies that fight off invading bacteria, viruses and other foreign substances. During ...