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Single-cell technique maps pre-malignant gene mutations in solid tissues

A new single-cell profiling technique has mapped pre-malignant gene mutations and their effects in solid tissues for the ...

Mapping gene disruptions in sporadic early onset Alzheimer's disease across key brain regions

A new study led by researchers at UTHealth Houston investigated both gene expression and regulation at single cell levels to reveal disruptions in gene function in three brain regions of patients with ...
GEN

Single-Cell Proteomics Reveal Hidden Layers of Gene Expression

Single cell gene expression studies often rely on single-cell RNA sequencing (scRNA-seq) alone. While scRNA-seq reveals which genes are turned on, it does not capture protein expression or changes to ...
EurekAlert!

Centromere protein I, a cell cycle checkpoint gene, accelerates tumor progression via the hippo pathway and mediates immune escape in hepatocellular carcinoma

Cell cycle checkpoint-related genes (CCCRGs) are implicated in the development and progression of hepatocellular carcinoma ...