PHILADELPHIA -- An oral, non-addictive sodium channel blocker safely relieved moderate-to-severe acute pain following surgery, according to phase III data that could support regulatory approval.

Addiction risks from opioid drugs come from their targeting of receptors found primarily in the central nervous system. Other pathways are associated with pain, but many research efforts to hit them ...

Steven Poelzing (left) and Gregory Hoeker, researchers at the Fralin Biomedical Research Institute at VTC, collaborated on a new study published in the journal Heart Rhythm revealing why low blood ...

Haisco Pharmaceutical Group Co. Ltd. has disclosed new tetrahydrofuran derivatives acting as sodium channel protein type 10 subunit alpha (SCN10A; Nav1.8) blockers reported to be useful for the ...

Nat Clin Pract Neurol. 2008;4(3):159-169. Drug Primary clinical use Protective effect during administration in animal models? Effects of withdrawal in EAE Clinical study Phenytoin Treatment of ...

Psoriasis, a common chronic immune-mediated inflammatory skin disorder, is characterized by excessive proliferation and abnormal differentiation of keratinocytes and dermal infiltration of immune ...

For most of us, pain is an unwelcome but vital warning system that tells us when something is wrong. However, for the small ...