Mechanistic model for MTOC maturation in GV oocytes. The MTOC (grey) activates near the oocyte cortex, which requires recruitment of CKAP5 and TACC3. After activation, MTOC migrates to the nuclear ...
Chromosome segregation during cell division is enacted by the mitotic ‘spindle’. Chromosomes connect to the spindle through kinetochores that capture microtubules and attach to their plus ends, the ...
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