Background and Aim: The current diagnostic methods for detecting Helicobacter pylori infection include rapid urease test (RUT), urea breath test (UBT), histology, culture, and serum antibody detection ...
Background. The development of an efficacious vaccine against infection with Helicobacter pylori, the causative agent of chronic gastritis, peptic ulcer disease, and gastric adenocarcinoma, remains a ...
Helicobacter pylori, a gram-negative spiral bacterium, is the cause of chronic superficial (type B) gastritis and peptic ulcer disease. The urease enzyme of H. pylori was expressed as an inactive ...
This article was published in Scientific American’s former blog network and reflects the views of the author, not necessarily those of Scientific American Urea is a small molecule formed as proteins ...
The study of urease inhibitors and molecular docking embodies a confluence of advanced synthetic chemistry, computational biology, and structural biochemistry. Urease, a nickel-dependent enzyme ...
There is general agreement that H. pylori infection is closely associated with chronic gastritic conditions, including intestinal metaplasia, peptic ulcer and gastric cancer. Several methods for ...