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An important step in the blood coagulation process is the enzymatic conversion of the protein prothrombin to the lower-molecular-weight clotting agent, thrombin, via cleavage of a portion of the prothrombin polypeptide. Prothrombin →thrombin cleaved peptide The values of s20, w and D20, w for prothrombin have been found to be 4.85  S and 6.24 ×10^-11  m^2  s^-1 respectively. The diffusion coefficient for thrombin is 8.76 ×10^-11  m^2  s^-1. Assuming that both thrombin and prothrombin are unhyd
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